Tenofovir alafenamide fumarate
Tenofovir Alafenamide fumarate
CAS: 1392275-56-7
Molecular Formula: C25H33N6O9P
Tenofovir alafenamide fumarate - Names and Identifiers
Tenofovir alafenamide fumarate - Physico-chemical Properties
| Molecular Formula | C25H33N6O9P |
| Molar Mass | 592.55 |
| Solubility | DMSO |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Use | This product is for scientific research only and shall not be used for other purposes. |
| In vitro study | Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) antiviral activities are similar across all cell types, ranging from 5 to 7 nM, while the CC 50 varies from 4.7 to 42 μM for MT-4 and MT-2 cells, respectively. The antiviral activity of TAF is evaluated against a panel of HIV-1 and HIV-2 isolates, including HIV-1 group M subtypes A to G, as well as group N and O isolates. Overall, for the 29 primary HIV-1 isolates tested in PBMCs, TAF EC 50 s range from 0.1 to 12 nM, with a mean EC 50 of 3.5 nM compared to a mean EC 50 of 11.8 nM for AZT, which is used as an internal control. For the HIV-2 isolates, the mean EC 50 s are 1.8 nM for TAF and 6.4 nM for AZT. |
| In vivo study | Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an amidate prodrug of Tenofovir with good oral bioavailability and increases plasma stability compared to Tenofovir disoproxil fumarate (TDF) . |
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Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: 17505222756
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Mobile: +86-17551318830
Wechat: 17505222756
CAS: 1392275-56-7
Tel: 17505222756
Email: pules.cn@gmail.com
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Product Name: Tenofovir Alafenamide fumarate Request for quotationCAS: 1392275-56-7
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
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Multiple SpecificationsSpot supply
Product Name: Tenofovir Alafenamide Hemifumarate(2:1) CRS Visit Supplier Webpage Request for quotationCAS: 1392275-56-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple SpecificationsSpot supply
Product Name: GS-7340 (hemifumarate) Visit Supplier Webpage Request for quotationCAS: 1392275-56-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Tenofovir Alafenamide fumarate Request for quotation
CAS: 1392275-56-7
Tel: 0531-88990216
Email: fairouz@sdsihuanpharm.com
Mobile: 13335127975
QQ: 824027327Send QQ message
CAS: 1392275-56-7
Tel: 0531-88990216
Email: fairouz@sdsihuanpharm.com
Mobile: 13335127975
QQ: 824027327
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